Martins, ElisabeteUrbano, JoanaLeite, SérgioPinto, AdrianaGarcia, RaquelBergantim, RuiRodrigues-Pereira, PedroCosta, Paulo PinhoOsório, HugoTavares, Isabel2020-05-052020-05-052019-11-27Eur J Case Rep Intern Med. 2019 Nov 27;6(12):001237. doi: 10.12890/2019_0012372284-2594http://hdl.handle.net/10400.18/6596Free PMC articleAmyloidosis is a group of disorders characterised by the accumulation of extracellular deposits of insoluble protein aggregates. Clinical management depends on the accurate identification of the amyloid precursor and underlying cause. We describe a rare case of apolipoprotein A-IV cardiac amyloidosis, the diagnosis of which required mass spectrometry-based proteomic analysis.Learning points: To be able to perform the differential diagnosis of cardiac amyloidosis subtypes using imaging methods, analytical results and tissue analysis.To recognise the added value of mass spectrometry (MS)-based proteomic analysisengAmyloidosisApolipoproteinCardiomyopathyHeart FailureImagingNuclear MedicineDoenças Genéticasjournal article10.12890/2019_001237