Botelho, M.C.Alves, H.Richter, J.2016-05-242018-06-012016-04-30Parasitol Res. 2016 Jul;115(7):2913-4. doi: 10.1007/s00436-016-5090-6. Epub 2016 Apr 30.0932-0113ESSN: 1432-1955http://hdl.handle.net/10400.18/3802Letter to the editorInfection with the human liver fluke Opisthorchis viverrini induces cancer of the bile ducts, cholangiocarcinoma (CCA). It was shown previously that O. viverrini-secreted proteins accelerate wound resolution in human cholangiocytes. Recombinant Ov-GRN-1 (O. viverrini-derived gene encoding granulin-like growth factor) induced angiogenesis and accelerated mouse wound healing. Given the striking similarities of wound healing and cancer progression, here we discuss the major implications of this finding for an infection-induced cancer of major public health significance in the developing world.engCholangiocarcinomaOpisthorchis viverriniTumor ProgressionWound Healingjournal article10.1007/s00436-016-5090-6