David, Susana2021-11-102022-01-012021-08-13Trends Genet. 2021 Dec;37(12):1056-1059. doi: 10.1016/j.tig.2021.07.009. Epub 2021 Aug 13.1362-4555http://hdl.handle.net/10400.18/7805Important factors contribute to a gained momentum in candidate gene association studies (CGAS) including the generalized use of NGS, growing opportunity for hospital-based research and availability of open-source databases and bioinformatics tools. This report summarizes the general principles and analytical methods as a guide to CGAS in today’s favorable context.engCandidate Gene Association StudiesGenetic EpidemiologyGenetic Association AnalysisCommon DiseasesComplex TraitsDoenças Genéticasjournal article10.1016/j.tig.2021.07.009