Bajanca Lavado, Maria PaulaPinto, MiguelCarvalho, Maria DinahJantarada Domingos, GonçaloMelo-Cristino, José2025-02-042025-02-042024-02-09Eur J Clin Microbiol Infect Dis. 2024 Apr;43(4):791-795. doi: 10.1007/s10096-024-04774-2. Epub 2024 Feb 90934-9723http://hdl.handle.net/10400.18/10329Brief ReportWe report for the first time in Portugal a serotype c Haemophilus influenzae isolated from an adult, with HIV-1 infection. Whole-genome sequencing characterized the isolate as clonal complex ST-7, albeit with a novel MLST (ST2754) due to a unique atpG profile. Integration of this genome with other available H. influenzae serotype c genomes from PubMLST revealed its overall genetic distinctiveness, with the closest related isolate being identified in France in 2020. This surveillance study, involving collaboration among hospitals and reference laboratory, successfully contributed to the identification and characterization of this rare serotype.engHaemophilus influenzaeMolecular serotypingSerotype cWhole-genome sequenceInfecções RespiratóriasPortugaljournal article10.1007/s10096-024-04774-238332396