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|Title: ||Prevalence and risk factors for Giardia duodenalis infection among children: A case study in Portugal|
|Authors: ||Júlio, Cláudia|
|Keywords: ||Giardia Duodenalis|
|Issue Date: ||Jan-2012|
|Publisher: ||BioMed Central|
|Citation: ||Parasit Vectors. 2012 Jan 27;5:22|
|Abstract: ||Background: Giardia duodenalis is a widespread parasite of mammalian species, including humans. The prevalence
of this parasite in children residing in Portugal is currently unknown. This study intended to estimate G. duodenalis
infection prevalence and identify possible associated risk factors in a healthy paediatric population living in the
District of the Portuguese capital, Lisbon.
Methods: Between February 2002 and October 2008, 844 children were randomly selected at healthcare centres
while attending the national vaccination program. A stool sample and a questionnaire with socio-demographic
data were collected from each child. Giardia infection was diagnosed by direct examination of stools and antigen
detection by ELISA.
Results: The population studied revealed a gender distribution of 52.8% male and 47.2% female. Age distribution
was 47.4% between 0-5 years and 52.6% between 6-15 years.
The prevalence of Giardia infection was 1.9% (16/844) when estimated by direct examination and increased to
6.8% (57/844) when ELISA results were added. The prevalence was higher among children aged 0-5 years (7.8%),
than among older children (5.8%), and was similar among genders (6.9% in boys and 6.5% in girls). The following
population-variables were shown to be associated risk factors for G. duodenalis infection: mother’s educational level
(odds ratio (OR)= 4.49; confidence interval (CI): 1.20-16.84), father’s educational level (OR = 12.26; CI: 4.08-36.82),
presence of Helicobacter pylori infection (OR = 1.82; CI: 1.05-3.15), living in houses with own drainage system (OR =
0.10; CI: 0.02-0.64) and reported household pet contact, especially with dogs (OR = 0.53; CI: 0.31-0.93).
Conclusion: The prevalence of giardiasis in asymptomatic children residing in the region of Lisbon is high. Several
risk factors were associated with Giardia prevalence and highlight the importance of parents’ education and
sanitation conditions in the children’s well being. The association between G. duodenalis and H. pylori seems an
important issue deserving further investigation in order to promote prevention or treatment strategies|
|Peer Reviewed: ||yes|
|Publisher version: ||http://www.parasitesandvectors.com/content/5/1/22|
|Appears in Collections:||DEP - Artigos em revistas internacionais|
DDI - Artigos em revistas internacionais
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