Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.18/5662
Título: Commentary: Theileria Parasites Secrete a Prolyl Isomerase to Maintain Host Leukocyte Transformation
Autor: Fernandes, Ruben
Ferreira, Stephanie
Botelho, Mónica C.
Palavras-chave: Schistosoma haematobium
Theileria
Cancer
miR-155
Parasites
Data: 27-Abr-2018
Editora: Frontiers Media
Citação: Front Med (Lausanne). 2018 Apr 27;5:120. doi: 10.3389/fmed.2018.00120. eCollection 2018.
Resumo: The genus Theileria comprises apicomplexan parasites that are tick-transmitted and infect ruminants with important trade and industry impact in endemic countries. Infectious agents build up elaborate machinery to work together by means of host cell pathways and takeover their genetic and epigenetic mechanisms to modify phenotypic status of host cells. Among the Apicomplexa phylum encompassing obligate intracellular parasites, the only genus that introduces its DNA into mammalian host cells is Theileria, which is known to cause veterinary and human diseases. Various species, including Theileria parva and Theileria annulata, infect leukocytes causing alterations in their phenotypes that are common with several cancers, remarkably immortalization, hyperproliferation, and spreading. (...)
Descrição: Free PMC Article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934426/pdf/fmed-05-00120.pdf
A commentary on: Theileria Parasites Secrete a Prolyl Isomerase to Maintain Host Leukocyte Transformation by Marsolier J, Perichon M, DeBarry JD, Villoutreix BO, Chluba J, Lopez T, et al. Nature (2015) 520:378–82. doi: 10.1038/nature14044
URI: http://hdl.handle.net/10400.18/5662
DOI: 10.3389/fmed.2018.00120
ISSN: 2296-858X)
Versão do Editor: https://www.frontiersin.org/articles/10.3389/fmed.2018.00120/full
Aparece nas colecções:DPSPDNT - Artigos em revistas internacionais

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