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Title: Emergence of β-lactamase-mediated resistance to oxyimino-β-lactams in Enterobacteriaceae isolates in various services in a single centre
Authors: Manageiro, Vera
Ferreira, Eugénia
Jones-Dias, Daniela
Louro, Deolinda
Pinto, Margarida
Diogo, José
Caniça, Manuela
Keywords: Resistência aos Antimicrobianos
Issue Date: 2012
Publisher: Elsevier
Citation: Diagn Microbiol Infect Dis. 2012;72:272-277
Abstract: We studied 193 Enterobacteriaceae isolates presenting diminished susceptibility to oxyimino-cephalosporins recovered in a Portuguese hospital (2004–2008). CTX-M-3 producers, firstly detected in Portugal, were associated with a Klebsiella pneumoniae microepidemic clone. Production of CTX-M–type enzymes (CTX-M-1/-3/-9/-14/-15/-32), age ≥65 years, and nosocomial infection were risk factors for higher nonsusceptibility to oxyimino-β-lactams. CMY-2 and DHA-1 β-lactamases were only identified in 1% of isolates.
Peer review: yes
ISSN: 0732-8893
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Appears in Collections:DDI - Artigos em revistas internacionais

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