Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.18/5395
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dc.contributor.authorGonçalves, Vânia-
dc.contributor.authorMatos, Paulo-
dc.contributor.authorHenriques, Andreia-
dc.contributor.authorPereira, Joana-
dc.contributor.authorJordan, Peter-
dc.date.accessioned2018-03-13T15:31:19Z-
dc.date.available2018-03-13T15:31:19Z-
dc.date.issued2017-10-
dc.identifier.citationEMJ Oncol. 2017;51[1]:45-46. Abstract review No. AR5pt_PT
dc.identifier.issnISSN-2054-619X-
dc.identifier.urihttp://hdl.handle.net/10400.18/5395-
dc.description.abstractThe expression of most genes in the human genome can yield >1 transcript through the process of alternative splicing of pre-messenger RNA. Alternatively spliced transcripts significantly increase the complexity of human gene products because they either influence transcript degradation levels or encode functional protein variants that differ in specific domains. Even with cutting-edge transcriptomic approaches, it has been extremely challenging to understand or predict the complex splicing patterns observed in tissues or in diseases such as cancer; therefore, a better understanding of how cells are able to regulate alternative splicing is required.pt_PT
dc.description.sponsorshipThis work was supported by the Fundação para a Ciência e Tecnologia through a centre grant (UID/MULTI/04046/2013) to BioISI, and by the Portuguese association Maratona da Saúde - Cancro 2014.pt_PT
dc.language.isoengpt_PT
dc.publisherEuropean Medical Journalpt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/5876/147256/PTpt_PT
dc.rightsopenAccesspt_PT
dc.subjectSignalling Pathwayspt_PT
dc.subjectAlternative Splicingpt_PT
dc.subjectRAC1bpt_PT
dc.subjectSplicing Alternativopt_PT
dc.subjectVias de Transdução de Sinal e Patologias Associadaspt_PT
dc.subjectCancro Coloretalpt_PT
dc.titleSignal transduction pathways regulating alternative splicing of tumour-related RAC1bpt_PT
dc.typearticlept_PT
dc.peerreviewednopt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
degois.publication.firstPage45pt_PT
degois.publication.lastPage46pt_PT
degois.publication.issue[1]pt_PT
degois.publication.titleEuropean Medical Journal Oncologypt_PT
degois.publication.volume5pt_PT
dc.relation.publisherversionhttp://www.emjreviews.com/oncology/abstract/signal-transduction-pathways-regulating-alternative-splicing-of-tumour-related-rac1b/pt_PT
Aparece nas colecções:DGH - Artigos em revistas internacionais

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