Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.18/5395
Título: Signal transduction pathways regulating alternative splicing of tumour-related RAC1b
Autor: Gonçalves, Vânia
Matos, Paulo
Henriques, Andreia
Pereira, Joana
Jordan, Peter
Palavras-chave: Signalling Pathways
Alternative Splicing
RAC1b
Splicing Alternativo
Vias de Transdução de Sinal e Patologias Associadas
Cancro Coloretal
Data: Out-2017
Editora: European Medical Journal
Citação: EMJ Oncol. 2017;51[1]:45-46. Abstract review No. AR5
Resumo: The expression of most genes in the human genome can yield >1 transcript through the process of alternative splicing of pre-messenger RNA. Alternatively spliced transcripts significantly increase the complexity of human gene products because they either influence transcript degradation levels or encode functional protein variants that differ in specific domains. Even with cutting-edge transcriptomic approaches, it has been extremely challenging to understand or predict the complex splicing patterns observed in tissues or in diseases such as cancer; therefore, a better understanding of how cells are able to regulate alternative splicing is required.
Peer review: no
URI: http://hdl.handle.net/10400.18/5395
ISSN: ISSN-2054-619X
Versão do Editor: http://www.emjreviews.com/oncology/abstract/signal-transduction-pathways-regulating-alternative-splicing-of-tumour-related-rac1b/
Aparece nas colecções:DGH - Artigos em revistas internacionais

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