Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.18/4232
Título: Mobile genetic elements associated to antibiotic resistance in Salmonella enterica isolates collected in food-chain
Autor: Manageiro, Vera
Gomes-Neves, Eduarda
Correia da Costa, José Manuel
Caniça, Manuela
Palavras-chave: Resistência aos Antibióticos
Data: Set-2014
Citação: Manageiro, V., Gomes-Neves, E., Correia da Costa, J. M., and Caniça, M. 2014. Mobile genetic elements associated to antibiotic resistance in Salmonella enterica isolates collected in food-chain. TEMPH 2014 - Trends in Environmental Microbiology for Public Health. Lisbon School of Health Technology, Lisbon, Portugal.
Resumo: In this study, we assessed the presence of IS26 elements in 60 multidrug resistant (R-type ASSuT phenotype) Salmonella enterica isolates collected in slaughtered swine samples in Portugal, investigating its role in the dissemination of antimicrobial resistance among different reservoirs. PCR-mapping allowed us to describe a new genetic organization, in the emergent Salmonella Rissen, including a peptidase C14 caspase catalytic subunit P20 gene between two IS26 elements. Furthermore, we detected the same genetic structures in Salmonella isolates from different serotypes in samples from slaughtered swine, carcasses/meat, and meat handlers, namely a resistance region harboring blaTEM-1 genes also flanked by 2 copies of IS26 elements in Salmonella Typhimurium (n=17) and Salmonella 4,[5],12:i:- variants (n=2). This study highlights that IS26 mobile genetic elements might play an important role in the mobilization of antibiotic resistance genes, which can constitutes a problem in terms of veterinary medicine and public health in general.
Peer review: yes
URI: http://hdl.handle.net/10400.18/4232
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