Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.18/4052
Título: Is there a relation between environmental exposure to teratogenic substances during pregnancy and congenital anomalies in the newborn? A pilot study in Portugal
Autor: Machado, Ausenda
Braz, Paula
Santos, Joana
Marques, Inês
Dias, Carlos Matias
Palavras-chave: RENAC
Congenital Anomalies
Environmental Exposure
Case Control Study
Determinantes da Saúde e da Doença
Anomalias Congénitas
Registo Nacional de Anomalias Congénitas
Data: Jun-2016
Editora: Instituto Nacional de Saúde Doutor Ricardo Jorge, IP
Resumo: Background: Maternal occupation as a proxy of environmental exposure has been consistently associated with specific congenital anomalies (CA) in the foetus and newborn. On the other hand, geographical location of the mother such as place of residence and place of work have not been used as proxy for environmental exposures during pregnancy. We designed a pilot study aiming to investigate the association between maternal place of residence and workplace during pregnancy and CA in Portugal. Methods: Cases and controls are identified in the maternity unit. Cases are all live births with at least one CA delivered in the Barreiro hospital located in a heavy industrial area near Lisboa. Controls are the two normal births following each case. Residents outside the study area, stillbirths and women who decline to participate or are incapable of giving consent are excluded. A health professional interviews the mothers using a questionnaire adapted from the registry form of the Portuguese national registry of CA and includes information on places during pregnancy (residence, workplace, leisure), and demographic characterization as place of birth, infant sex, weight, description of CA, age of mother, ethnicity, maternal birth place. Maternal health and obstetric history, education, smoking, alcohol, drugs and medication use is also collected as potential confounders. Results: The pilot study started in January 2016 and at the moment two cases and four controls have been recruited without refusals. The study will continue to be implemented and it is proposed to start in other hospital units during 2016.
Peer review: yes
URI: http://hdl.handle.net/10400.18/4052
Aparece nas colecções:DEP - Posters/abstracts em congressos internacionais

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