Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.18/4035
Título: Bacterial biofilms, antibiotic resistance and healthcare-associated infections: a dangerous connection
Autor: Bandeira, Maria
Carvalho, Patricia Almeida
Duarte, Aida
Jordao, Luisa
Palavras-chave: Biofilms
Antibiotic Resistance
Healthcare-associated Infections (HAI)
Data: 10-Set-2015
Editora: Cambridge Journals Press/Microscopy Society of America
Citação: Microsc. Microanal.2015;21(Suppl 6):38-39
Resumo: In 2012, were estimated 6.7 million cases of healthcare-associated infections (HAI) either in long-term care facilities or acute-care hospitals from which result 37,000 deaths configuring a serious public health problem. The etiological agents are diverse and often resistant to antimicrobial drugs. One of the mechanisms responsible for the emergence of drug resistance is biofilm assembly. Biofilms are defined as thin layers of microorganisms adhering to the surface of a structure, which may be organic or inorganic, together with the polymers that they secrete. They are dynamic structures which experience different stages of organization with the ageing and are linked to an increase in bacterial resistance to host defense mechanisms, antibiotics, sterilization procedures other than autoclaving, persistence in water distribution systems and other surfaces. The understanding of bacteria organization within the biofilm and the identification of differences between planktonic and sessile forms of bacteria will be a step forward to fight HAIs.
Peer review: yes
URI: http://hdl.handle.net/10400.18/4035
DOI: 10.1017/S1431927614013865
ISSN: 1431-9276
Versão do Editor: https://www.cambridge.org/core/journals/microscopy-and-microanalysis/article/bacterial-biofilms-antibiotic-resistance-and-healthcare-associated-infections-a-dangerous-connection/4F044E7A00E2E2B9FB7BCBFA6E155CCD
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