Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.18/2460
Título: Characterization of a Population Concerning Vitamins and Anemia Biomarkers
Autor: Mota, Carla
Tavares, Nuno
Torres, Duarte
Santos, Mariana
Castanheira, Isabel
Matos, Ana Sofia
Palavras-chave: Composição de Alimentos
Vitamin B12
Cluster Analysis
Data: Set-2014
Editora: Instituto Nacional de Saúde Doutor Ricardo Jorge, IP
Resumo: Folate, vitamin B12, iron and hemoglobin are essential for metabolic functions. Deficiency of these can cause several known pathologies and, untreated, severe morbidity and death. The objective of this study is to characterize a population, concerning serum levels of folate, B12, iron and hemoglobin, as well as finding evidence of correlations between these parameters and illnesses, mainly cardiovascular, gastrointestinal, neurological and anemia. The laboratorial data collected consists of blood analysis in patients, required by the patients’ doctors, and were retrieved in 2012. The total population consisted of 728 individuals, residing in Lisbon metropolitan area in Portugal. When coming in for examination, the patients were asked routine questions about their age, gender, county of residence, reason for examination and what medication or supplementation they were taking. The population consisted of 140 male patients and 588 female patients, aged from 2 to 95 years of age. There are 329 persons over 60 years old, these are considered elderly patients. Clinical data was submitted to multivariate analysis. The data was screened with Spearman correlation and Kruskal-Wallis analysis of variance to study correlations and variability between groups. To characterize the population, we used cluster analysis with Ward’s linkage method. A positive correlation between iron with, ferritin and transferrin, and with hemoglobin was observed with the Spearman correlation. Kruskal-Wallis analysis of variance showed significant differences between these biomarkers in persons aged 0-29, 30-59 and over 60 years old. Cluster analysis, evidence low folate levels for population in general, and hemoglobin levels below the reference values for 42.8% of study population. Iron and vitamin B12 were within the reference range for most of the population. Low levels of the parameters were registered mainly in cardiovascular, gastrointestinal, neurological diseases and anemia patients.
Descrição: Abstract publicado em:"Book of Abstracts",(nº100).
Peer review: yes
URI: http://hdl.handle.net/10400.18/2460
Aparece nas colecções:DAN - Posters/abstracts em congressos internacionais

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