Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.18/2068
Título: Trends in influenza vaccination coverage in Portugal from 1998 to 2010: effect of major pandemic threats
Autor: Sousa Pinto, Cátia
Nunes, Baltazar
Branco, Maria João
Marinho Falcão, José
Palavras-chave: influenza
Vaccine Coverage
Vaccination Trends
Estado da Saude e da Doença
Data: 5-Dez-2013
Editora: BioMed Central
Citação: BMC Public Health. 2013;13:1130. doi: 10.1186/1471-2458-13-1130
Resumo: BACKGROUND: Vaccination is the key measure available for prevention of the public health burden of annual influenza epidemics. This article describes national trends in seasonal influenza vaccine (IV) coverage in Portugal from 1998/99 to 2010/11, analyzes progress towards meeting WHO 2010 coverage goals, and addresses the effect of major public health threats of the last 12 years (SARS in 2003/04, influenza A (H5N1) in 2005/06, and the influenza A (H1N1)2009 pandemic) on vaccination trends. METHODS: The National Institute of Health surveyed (12 times) a random sample of Portuguese families. IV coverage was estimated and was adjusted for age distribution and country region. Independence of age and sex coverage distribution was tested using a modified F-statistic with a 5% significance level. The effect of SARS, A (H5N1), and the A (H1N1)2009 pandemic was tested using a meta-regression model. The model was adjusted for IV coverage in the general population and in the age groups. RESULTS: Between 1998/99 and 2010/11 IV, coverage in the general population varied between 14.2% (CI(95%): 11.6%-16.8%) and 17.5% (CI(95%): 17.6%-21.6%). There was no trend in coverage (p = 0.097). In the younger age group (<15 years) a declining trend was identified until 2008/09 (p = 0.005). This trend reversed in 2009/10. There was also a gradual and significant increase in seasonal IV coverage in the elderly (p for trend < 0.001). After 2006/07, IV coverage remained near 50%. Adjusting for baseline trends, there was significantly higher coverage in the general population in 2003/04 (p = 0.032) and 2005/06 (p = 0.018). The high coverage observed in the <15-year age group in season 2009/10 was also significant (p = 0.015). CONCLUSIONS: IV coverage in the elderly population displayed an increasing trend, but the 75% WHO 2010 target was not met. This result indicates that influenza vaccination strategy should be improved to meet the ambitious WHO coverage goals. The major pandemic threats of the past decade had a modest but significant effect on seasonal influenza vaccination. There was an increase in vaccine uptake proportion in the general population in 2003/04 and in 2005/06, and in individuals <15 years old in 2009/10.
Peer review: yes
URI: http://hdl.handle.net/10400.18/2068
ISSN: 1471-2458
doi: 10.1186/1471-2458-13-1130
Versão do Editor: http://www.biomedcentral.com/1471-2458/13/1130
Aparece nas colecções:DEP - Artigos em revistas internacionais

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