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|Title:||New Delhi metallo-beta-lactamase 1-producing Enterobacteriaceae: emergence and response in Europe|
|Authors:||Struelens, M. J.|
Monnet, D. L.
Magiorakos, A. P.
O’Connor, F. Santos
Giesecke, J .
The European NDM-1 Survey Participants
Resistência aos Antimicrobianos
|Publisher:||European Centre for Disease Prevention and Control|
|Citation:||Euro Surveill. 2010 Nov 18;15(46). pii: 19716|
|Abstract:||Acquired carbapenemases confer extensive antibiotic resistance to Enterobacteriaceae and represent a public health threat. A novel acquired carbapenemase, New Delhi metallo-beta-lactamase 1 (NDM-1), has recently been described in the United Kingdom and Sweden, mostly in patients who had received care on the Indian subcontinent. We conducted a survey among 29 European countries (the European Union Member States, Iceland and Norway) to gather information on the spread of NDM-1-producing Enterobacteriaceae in Europe, on public health responses and on available national guidance on detection, surveillance and control. A total of 77 cases were reported from 13 countries from 2008 to 2010. Klebsiella pneumoniae was the most frequently reported species with 54%. Among 55 cases with recorded travel history, 31 had previously travelled or been admitted to a hospital in India or Pakistan and five had been hospitalised in the Balkan region. Possible nosocomial acquisition accounted for 13 of 77 cases. National guidance on NDM-1 detection was available in 14 countries and on NDM-1 control in 11 countries. In conclusion, NDM-1 is spreading across Europe, where it is frequently linked to a history of healthcare abroad, but also to emerging nosocomial transmission. National guidance in response to the threat of carbapenemase-producing Enterobacteriaceae is available in approximately half of the surveyed European countries. Surveillance of carbapenemase- producing Enterobacteriaceae must be enhanced in Europe and effective control measures identified and implemented.|
|Description:||The European NDM-1 Survey Participants: Manuela Caniça (Departamento de Doenças Infecciosas do INSA)|
|Appears in Collections:||DDI - Artigos em revistas internacionais|
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