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Repositório Científico do Instituto Nacional de Saúde >
Departamento de Promoção da Saúde e Prevenção de Doenças Não Transmissíveis >
DPSPDNT - Artigos em revistas internacionais >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10400.18/172
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| Title: | Association of a genetic variant in the ALOX5AP with higher risk of ischemic stroke: a case-control, meta-analysis and functional study |
| Authors: | Domingues-Montanari, S.
Fernández-Cadenas, I.
Del Rio-Espinola, A.
Corbeto, N.
Krug, T.
Manso, H.
Gouveia, L.
Sobral, J.
Mendioroz, M.
Fernández-Morales, J.
Alvarez-Sabin, J.
Ribó, M.
Rubiera, M.
Obach, V.
Martí-Fàbregas, J.
Freijo, M.
Serena, J.
Ferro, J.M.
Vicente, A.M.
Oliveira, S.A.
Montaner, J. |
| Keywords: | ALOX5AP
Single nucleotide polymorphism
Meta-analysis
Stroke
Genetics
PDE4D
Doenças Cardio e Cérebro-vasculares |
| Issue Date: | May-2010 |
| Publisher: | Karger |
| Citation: | Cerebrovasc Dis. 2010;29(6):528-37. Epub 2010 Mar 30. |
| Abstract: | Variants in the 5-lipoxygenase-activating protein (ALOX5AP) and phosphodiesterase 4D (PDE4D) genes have first been associated with ischemic stroke (IS) through whole-genome linkage screens. However, association studies obtained conflicting results. We aimed to investigate the contribution of selected single nucleotide polymorphisms (SNPs) in these genes for the first time in a large Iberian population. |
| Peer Reviewed: | yes |
| URI: | http://hdl.handle.net/10400.18/172 |
| ISSN: | 1015-9770 |
| Publisher version: | http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowFulltext&ArtikelNr=302738&Ausgabe=254017&ProduktNr=224153 |
| Appears in Collections: | DPSPDNT - Artigos em revistas internacionais
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