http://hdl.handle.net/10400.18/3 2013-05-19T14:22:00Z http://hdl.handle.net/10400.18/1568 Title: Evolução temporal da idade à data de diagnóstico de infeção VIH/SIDA em Portugal: 1983-2012 Authors: Martins, Helena Cortes; Kislaya, Irina; Nunes, Baltazar 2013-04-08T00:00:00Z http://hdl.handle.net/10400.18/1556 Title: À descoberta dos avós Authors: Departamento de Epidemiologia Abstract: Apresentação de atividade relativa aos determinantes para o envelhecimento ativo no decorrer da semana aberta proposta pelo INSA, IP em 2012. Description: Folheto entregue aos alunos que efectuaram a visita. 2012-03-19T00:00:00Z http://hdl.handle.net/10400.18/1555 Title: Spectrum of congenital anomalies in pregnancies with pregestational diabetes Authors: Garne, Ester; Loane, Maria; Dolk, Helen; Barisic, Ingeborg; Addor, Marie-Claude; Arriola, Larraitz; Bakker, Marian; Calzolari, Elisa; Dias, Carlos Matias; Doray, Berenice; Gatt, Miriam; Melve, Kari Klyungsoyr; Nelen, Vera; O’Mahony, Mary; Pierini, Anna; Randrianaivo-Ranjatoelina, Hanitra; Rankin, Judith; Rissmann, Anke; Tucker, David; Verellun-Dumoulin, Christine; Wiesel, Awi Abstract: Maternal pregestational diabetes is a well-known risk factor for congenital anomalies. This study analyses the spectrum of congenital anomalies associated with maternal diabetes using data from a large European database for the population-based surveillance of congenital anomalies. METHODS: Data from 18 population-based EUROCAT registries of congenital anomalies in 1990-2005. All malformed cases occurring to mothers with pregestational diabetes (diabetes cases) were compared to all malformed cases in the same registry areas to mothers without diabetes (non-diabetes cases). RESULTS: There were 669 diabetes cases and 92,976 non diabetes cases. Odds ratios in diabetes pregnancies relative to non-diabetes pregnancies comparing each EUROCAT subgroup to all other non-chromosomal anomalies combined showed significantly increased odds ratios for neural tube defects (anencephaly and encephalocele, but not spina bifida) and several subgroups of congenital heart defects. Other subgroups with significantly increased odds ratios were anotia, omphalocele and bilateral renal agenesis. Frequency of hip dislocation was significantly lower among diabetes (odds ratio 0.15, 95% CI 0.05–0.39) than non-diabetes cases. Multiple congenital anomalies were present in 13.6 % of diabetes cases and 6.1 % of non-diabetes cases. The odds ratio for caudal regression sequence was very high (26.40, 95% CI 8.98–77.64), but only 17% of all caudal regression cases resulted from a pregnancy with pregestational diabetes. CONCLUSIONS: The increased risk of congenital anomalies in pregnancies with pregestational diabetes is related to specific non-chromosomal congenital anomalies and multiple congenital anomalies and not a general increased risk. 2012-03-01T00:00:00Z http://hdl.handle.net/10400.18/1554 Title: Ano europeu do envelhecimento ativo e solidariedade entre gerações - à descoberta dos Avós Authors: Departamento de Epidemiologia Abstract: Iniciativa no âmbito do Ano europeu do envelhecimento ativo e solidariedade entre gerações. 2012-03-19T00:00:00Z